Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery

BACKGROUND: Hepatocellular carcinoma (HCC) is a malignant tumor that threatens global human health. High PKM2 expression is widely reported in multiple cancers, especially in HCC. This study aimed to explore the effects of PKM2 on global gene expression, metabolic damages, patient prognosis, and mul...

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Detalles Bibliográficos
Autores principales: Lv, Wen-Wen, Liu, Dahai, Liu, Xing-Cun, Feng, Tie-Nan, Li, Lei, Qian, Bi-Yun, Li, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249977/
https://www.ncbi.nlm.nih.gov/pubmed/30463528
http://dx.doi.org/10.1186/s12885-018-5023-0

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