Regulation of MRTF-A by JMY via a nucleation-independent mechanism

BACKGROUND: MRTF-A (myocardin-related transcription factor A) is a coactivator for SRF-mediated gene expression. The activity of MRTF-A is critically dependent on the dissociation of G-actin from N-terminal RPEL motifs. MRTF-SRF induction often correlates with enhanced polymerization of F-actin. Her...

Descripción completa

Detalles Bibliográficos
Autores principales: Kluge, Franziska, Weissbach, Julia, Weber, Anja, Stradal, Theresia, Posern, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249979/
https://www.ncbi.nlm.nih.gov/pubmed/30463620
http://dx.doi.org/10.1186/s12964-018-0299-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249979/
https://www.ncbi.nlm.nih.gov/pubmed/30463620
http://dx.doi.org/10.1186/s12964-018-0299-x

Ejemplares similares