Comparison of Rearranged During Transfection (RET) Gene Rearrangements in Primary Versus Metastatic Non-Small Cell Lung Cancer (NSCLC)

BACKGROUND: RET rearrangements have been reported in 30% of papillary thyroid carcinomas and 1–2% of non-small cell lung cancer (NSCLC). In these tumors, RET gene fusion product provides a constitutively active tyrosine kinase (TKR), leading to uncontrolled cellular proliferation, differentiation, a...

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Detalles Bibliográficos
Autores principales: Zhang, Quxia, Xu, Chunwei, Wang, Wenxian, Wu, Meijuan, Zhu, Youcai, Zhuang, Wu, Du, Kaiqi, Huang, Yunjian, Chen, Yanping, Wu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249982/
https://www.ncbi.nlm.nih.gov/pubmed/30429449
http://dx.doi.org/10.12659/MSM.911634

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