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Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population

AIMS: To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS: A population-based study was conducted. T2DM and undiagnosed T2...

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Autores principales: Bernabe-Ortiz, Antonio, Perel, Pablo, Miranda, Juan Jaime, Smeeth, Liam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249987/
https://www.ncbi.nlm.nih.gov/pubmed/30131300
http://dx.doi.org/10.1016/j.pcd.2018.07.015
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author Bernabe-Ortiz, Antonio
Perel, Pablo
Miranda, Juan Jaime
Smeeth, Liam
author_facet Bernabe-Ortiz, Antonio
Perel, Pablo
Miranda, Juan Jaime
Smeeth, Liam
author_sort Bernabe-Ortiz, Antonio
collection PubMed
description AIMS: To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS: A population-based study was conducted. T2DM and undiagnosed T2DM were defined using oral glucose tolerance test (OGTT). Risk scores assessed were FINDRISC, LA-FINDRISC and Peruvian Risk Score. Diagnostic accuracy of risk scores was estimated using the c-statistic and the area under the ROC curve (aROC). A simplified version of FINDRISC was also derived. RESULTS: Data from 1609 individuals, mean age 48.2 (SD: 10.6), 810 (50.3%) women, were collected. A total of 176 (11.0%; 95%CI: 9.4%–12.5%) were classified as having T2DM, and 71 (4.7%; 95%CI: 3.7%–5.8%) were classified as having undiagnosed T2DM. Diagnostic accuracy of the FINDRISC (aROC = 0.69), LA-FINDRISC (aROC = 0.68), and Peruvian Risk Score (aROC = 0.64) was similar (p = 0.15). The simplified FINDRISC, with 4 variables, had a slightly better performance (aROC = 0.71) than the other scores. CONCLUSION: The performance of FINDRISC, LA-FINDRISC and Peruvian Risk Score for undiagnosed T2DM was similar. A simplified FINDRISC can perform as well or better for undiagnosed T2DM. The FINDRISC may be useful to detect cases of undiagnosed T2DM in resource-constrained settings.
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spelling pubmed-62499872018-12-01 Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population Bernabe-Ortiz, Antonio Perel, Pablo Miranda, Juan Jaime Smeeth, Liam Prim Care Diabetes Article AIMS: To assess the diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM and to compare its performance with the Latin-American FINDRISC (LA-FINDRISC) and the Peruvian Risk Score. MATERIALS AND METHODS: A population-based study was conducted. T2DM and undiagnosed T2DM were defined using oral glucose tolerance test (OGTT). Risk scores assessed were FINDRISC, LA-FINDRISC and Peruvian Risk Score. Diagnostic accuracy of risk scores was estimated using the c-statistic and the area under the ROC curve (aROC). A simplified version of FINDRISC was also derived. RESULTS: Data from 1609 individuals, mean age 48.2 (SD: 10.6), 810 (50.3%) women, were collected. A total of 176 (11.0%; 95%CI: 9.4%–12.5%) were classified as having T2DM, and 71 (4.7%; 95%CI: 3.7%–5.8%) were classified as having undiagnosed T2DM. Diagnostic accuracy of the FINDRISC (aROC = 0.69), LA-FINDRISC (aROC = 0.68), and Peruvian Risk Score (aROC = 0.64) was similar (p = 0.15). The simplified FINDRISC, with 4 variables, had a slightly better performance (aROC = 0.71) than the other scores. CONCLUSION: The performance of FINDRISC, LA-FINDRISC and Peruvian Risk Score for undiagnosed T2DM was similar. A simplified FINDRISC can perform as well or better for undiagnosed T2DM. The FINDRISC may be useful to detect cases of undiagnosed T2DM in resource-constrained settings. Elsevier 2018-12 /pmc/articles/PMC6249987/ /pubmed/30131300 http://dx.doi.org/10.1016/j.pcd.2018.07.015 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bernabe-Ortiz, Antonio
Perel, Pablo
Miranda, Juan Jaime
Smeeth, Liam
Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title_full Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title_fullStr Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title_full_unstemmed Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title_short Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
title_sort diagnostic accuracy of the finnish diabetes risk score (findrisc) for undiagnosed t2dm in peruvian population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249987/
https://www.ncbi.nlm.nih.gov/pubmed/30131300
http://dx.doi.org/10.1016/j.pcd.2018.07.015
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