Cargando…

From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic

Hospitals worldwide are facing an increasing incidence of hard-to-treat infections. Limiting infections and providing patients with optimal drug regimens require timely strain identification as well as virulence and drug-resistance profiling. Additionally, prophylactic interventions based on the ide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Balloux, Francois, Brønstad Brynildsrud, Ola, van Dorp, Lucy, Shaw, Liam P., Chen, Hongbin, Harris, Kathryn A., Wang, Hui, Eldholm, Vegard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Trends Journals 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249990/ https://www.ncbi.nlm.nih.gov/pubmed/30193960 http://dx.doi.org/10.1016/j.tim.2018.08.004

Ejemplares similares

Rapid phenotypic evolution in multidrug-resistant Klebsiella pneumoniae hospital outbreak strains
por: van Dorp, Lucy, et al.
Publicado: (2019)

Antibiotic Treatment Regimes as a Driver of the Global Population Dynamics of a Major Gonorrhea Lineage
por: Osnes, Magnus N, et al.
Publicado: (2020)

Corrigendum to: Antibiotic Treatment Regimes as a Driver of the Global Population Dynamics of a Major Gonorrhea Lineage
por: Osnes, Magnus N, et al.
Publicado: (2022)

Gauging the epidemic potential of a widely circulating non-invasive meningococcal strain in Africa
por: Brynildsrud, Ola Brønstad, et al.
Publicado: (2019)

Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa
por: Brynildsrud, Ola Brønstad, et al.
Publicado: (2018)

Genomic epidemiology and population structure of Neisseria gonorrhoeae in Norway, 2016–2017
por: Alfsnes, Kristian, et al.
Publicado: (2020)

Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary
por: Brynildsrud, Ola, et al.
Publicado: (2016)

Erratum to: Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary
por: Brynildsrud, Ola, et al.
Publicado: (2016)

Naturally occurring Neisseria gonorrhoeae can have large deletions in housekeeping gene abcZ, making them untypable with multilocus sequence typing
por: Vollan, Hilde Synnøve, et al.
Publicado: (2022)

Modeling of the GC content of the substituted bases in bacterial core genomes
por: Bohlin, Jon, et al.
Publicado: (2018)

The nucleotide composition of microbial genomes indicates differential patterns of selection on core and accessory genomes
por: Bohlin, Jon, et al.
Publicado: (2017)

Q&A: What are pathogens, and what have they done to and for us?
por: Balloux, Francois, et al.
Publicado: (2017)

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
por: van Dorp, Lucy, et al.
Publicado: (2020)

A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis
por: Alfsnes, Kristian, et al.
Publicado: (2018)

Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain
por: Eldholm, Vegard, et al.
Publicado: (2015)

Whole genome sequencing reveals within-host genetic changes in paired meningococcal carriage isolates from Ethiopia
por: Bårnes, Guro K., et al.
Publicado: (2017)

Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene bla(NDM)
por: Acman, Mislav, et al.
Publicado: (2022)

The effect of recombination on the evolution of a population of Neisseria meningitidis
por: MacAlasdair, Neil, et al.
Publicado: (2021)

Characterizing the virome of Ixodes ricinus ticks from northern Europe
por: Pettersson, John H.-O., et al.
Publicado: (2017)

Clinical sequencing: is WGS the better WES?
por: Meienberg, Janine, et al.
Publicado: (2016)

PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
por: Deshwar, Amit G, et al.
Publicado: (2015)

Whole genome sequencing (WGS) for food-borne pathogen surveillance and control – taking the pulse
por: Moran-Gilad, Jacob
Publicado: (2017)

Large-scale network analysis captures biological features of bacterial plasmids
por: Acman, Mislav, et al.
Publicado: (2020)

COVID-19, the first pandemic in the post-genomic era
por: van Dorp, Lucy, et al.
Publicado: (2021)

Clinical diagnostic whole genome sequencing in a paediatric population: experience from our WGS genetics clinic
por: Worthey, Elizabeth, et al.
Publicado: (2012)

A Whole Genome Sequencing (WGS) Approach to Predict Daptomycin (DAP) Susceptibility of Enterococcus faecium
por: Contreras, German, et al.
Publicado: (2017)

Digital-WGS: Automated, highly efficient whole-genome sequencing of single cells by digital microfluidics
por: Ruan, Qingyu, et al.
Publicado: (2020)

Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis
por: Eldholm, Vegard, et al.
Publicado: (2016)

Metagenomic evidence for a polymicrobial signature of sepsis
por: Tan, Cedric Chih Shen, et al.
Publicado: (2021)

Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice
por: Imperial, Robin, et al.
Publicado: (2019)

2298. Identifying and Addressing Implementation Barriers to Whole-Genome Sequencing (WGS) in State Public Health Laboratories
por: Oliver, Angela, et al.
Publicado: (2018)

Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture
por: Nimmo, Camus, et al.
Publicado: (2019)

GT-WGS: an efficient and economic tool for large-scale WGS analyses based on the AWS cloud service
por: Wang, Yiqi, et al.
Publicado: (2018)

A Practical Bioinformatics Workflow for Routine Analysis of Bacterial WGS Data
por: Atxaerandio-Landa, Aitor, et al.
Publicado: (2022)

Evolution and emergence of multidrug-resistant Mycobacterium tuberculosis in Chisinau, Moldova
por: Brown, Tyler S., et al.
Publicado: (2021)

Correction to: Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture
por: Nimmo, Camus, et al.
Publicado: (2019)

Bezlotoxumab (BEZ) for Prevention of Clostridium difficile Infection (CDI) Recurrence (rCDI): Distinguishing Relapse from Reinfection with Whole Genome Sequencing (WGS)
por: Dorr, Mary Beth, et al.
Publicado: (2017)

PulseNet International: Vision for the implementation of whole genome sequencing (WGS) for global food-borne disease surveillance
por: Nadon, Celine, et al.
Publicado: (2017)

Whole-Genome Shotgun (WGS) Sequence of cis-Isoprene Polymer-Degrading Nocardia sp. strain BSTN01
por: Sarkar, Biraj, et al.
Publicado: (2022)

Indikationsprüfung bei Patienten in Intensiv-WGs
por: Lux, Eberhard Albert, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iqqjtjtog1mcpo7qgr1tp0am7v