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Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats
OBJECTIVE: Fibrates are used as lipid-lowering drugs and are well tolerated as cotreatments when glucose metabolism disturbances are also present. Synthetic glucocorticoids (GCs) are diabetogenic drugs that cause dyslipidemia, dysglycemia, glucose intolerance, and insulin resistance when in excess....
Autores principales: | Inácio, Maiara Destro, Rafacho, Alex, de Paula Camaforte, Nathália Aparecida, Teixeira, Poliana, Vareda, Priscilla Maria Ponce, Violato, Natália Moretti, Bosqueiro, José Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250034/ https://www.ncbi.nlm.nih.gov/pubmed/30532777 http://dx.doi.org/10.1155/2018/3257812 |
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