Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats

OBJECTIVE: Fibrates are used as lipid-lowering drugs and are well tolerated as cotreatments when glucose metabolism disturbances are also present. Synthetic glucocorticoids (GCs) are diabetogenic drugs that cause dyslipidemia, dysglycemia, glucose intolerance, and insulin resistance when in excess....

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Detalles Bibliográficos
Autores principales: Inácio, Maiara Destro, Rafacho, Alex, de Paula Camaforte, Nathália Aparecida, Teixeira, Poliana, Vareda, Priscilla Maria Ponce, Violato, Natália Moretti, Bosqueiro, José Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250034/
https://www.ncbi.nlm.nih.gov/pubmed/30532777
http://dx.doi.org/10.1155/2018/3257812

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