Cargando…

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively

Hypoxia plays a crucial role at cellular and physiological levels in all animals. The responses to chronic hypoxia are, at least substantially, orchestrated by activation of the hypoxia inducible transcription factors (HIFs), whose stability and subsequent transcriptional activation are regulated by...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yihua, Zhong, Shan, Schofield, Christopher J., Ratcliffe, Peter J., Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250434/
https://www.ncbi.nlm.nih.gov/pubmed/30333145
http://dx.doi.org/10.1242/jcs.219782