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In-depth validation of total HIV-1 DNA assays for quantification of various HIV-1 subtypes

HIV-1 DNA quantification serves as an important reservoir biomarker in HIV cure trials. However, the high genetic diversity of HIV-1 represented by different subtypes may bring inaccuracy in quantifying HIV-1 DNA and a sensitive and validated assay covering diverse HIV-1 subtypes is lacking. Therefo...

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Detalles Bibliográficos
Autores principales:	Rutsaert, Sofie, De Spiegelaere, Ward, Van Hecke, Clarissa, De Scheerder, Marie-Angélique, Kiselinova, Maja, Vervisch, Karen, Trypsteen, Wim, Vandekerckhove, Linos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250682/ https://www.ncbi.nlm.nih.gov/pubmed/30467426 http://dx.doi.org/10.1038/s41598-018-35403-6

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