Effects of Modulating Actin Dynamics on HER2 Cancer Cell Motility and Metastasis

Amplification of HER2 leads to development of HER2-positive (HER2+) cancers with high rates of metastasis compared to other cancer subtypes. The goal of this study was to probe the vulnerability of HER2+ cancer cells to a filamentous actin (F-actin) severing and capping toxin. The growth and viabili...

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Detalles Bibliográficos
Autores principales: Nersesian, Sarah, Williams, Rodette, Newsted, Daniel, Shah, Kavan, Young, Stephanie, Evans, P. Andrew, Allingham, John S., Craig, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250728/
https://www.ncbi.nlm.nih.gov/pubmed/30467396
http://dx.doi.org/10.1038/s41598-018-35284-9

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