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c-Abl Inhibition Exerts Symptomatic Antiparkinsonian Effects Through a Striatal Postsynaptic Mechanism

Parkinson’s disease (PD) is caused by a progressive degeneration of nigral dopaminergic cells leading to striatal dopamine deficiency. From the perspective of antiparkinsonian drug mechanisms, pharmacologic treatment of PD can be divided into symptomatic and disease-modifying (neuroprotective) thera...

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Detalles Bibliográficos
Autores principales:	Zhou, Yu, Yamamura, Yukio, Ogawa, Masatoshi, Tsuji, Ryosuke, Tsuchiya, Koichiro, Kasahara, Jiro, Goto, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250819/ https://www.ncbi.nlm.nih.gov/pubmed/30505273 http://dx.doi.org/10.3389/fphar.2018.01311

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