Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia

Malaria and anaemia are key underlying factors for iNTS disease in African children. Knowledge of clinical and epidemiological risk-factors for iNTS disease has not been paralleled by an in-depth knowledge of the immunobiology of the disease. Herein, we review human and animal studies on mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Nyirenda, Tonney S., Mandala, Wilson L., Gordon, Melita A., Mastroeni, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250906/
https://www.ncbi.nlm.nih.gov/pubmed/29248635
http://dx.doi.org/10.1016/j.micinf.2017.11.014
_version_ 1783373005119815680
author Nyirenda, Tonney S.
Mandala, Wilson L.
Gordon, Melita A.
Mastroeni, Pietro
author_facet Nyirenda, Tonney S.
Mandala, Wilson L.
Gordon, Melita A.
Mastroeni, Pietro
author_sort Nyirenda, Tonney S.
collection PubMed
description Malaria and anaemia are key underlying factors for iNTS disease in African children. Knowledge of clinical and epidemiological risk-factors for iNTS disease has not been paralleled by an in-depth knowledge of the immunobiology of the disease. Herein, we review human and animal studies on mechanisms of increased susceptibility to iNTS in children.
format Online
Article
Text
id pubmed-6250906
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-62509062018-11-30 Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia Nyirenda, Tonney S. Mandala, Wilson L. Gordon, Melita A. Mastroeni, Pietro Microbes Infect Article Malaria and anaemia are key underlying factors for iNTS disease in African children. Knowledge of clinical and epidemiological risk-factors for iNTS disease has not been paralleled by an in-depth knowledge of the immunobiology of the disease. Herein, we review human and animal studies on mechanisms of increased susceptibility to iNTS in children. Elsevier 2018 /pmc/articles/PMC6250906/ /pubmed/29248635 http://dx.doi.org/10.1016/j.micinf.2017.11.014 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Nyirenda, Tonney S.
Mandala, Wilson L.
Gordon, Melita A.
Mastroeni, Pietro
Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title_full Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title_fullStr Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title_full_unstemmed Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title_short Immunological bases of increased susceptibility to invasive nontyphoidal Salmonella infection in children with malaria and anaemia
title_sort immunological bases of increased susceptibility to invasive nontyphoidal salmonella infection in children with malaria and anaemia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250906/
https://www.ncbi.nlm.nih.gov/pubmed/29248635
http://dx.doi.org/10.1016/j.micinf.2017.11.014
work_keys_str_mv AT nyirendatonneys immunologicalbasesofincreasedsusceptibilitytoinvasivenontyphoidalsalmonellainfectioninchildrenwithmalariaandanaemia
AT mandalawilsonl immunologicalbasesofincreasedsusceptibilitytoinvasivenontyphoidalsalmonellainfectioninchildrenwithmalariaandanaemia
AT gordonmelitaa immunologicalbasesofincreasedsusceptibilitytoinvasivenontyphoidalsalmonellainfectioninchildrenwithmalariaandanaemia
AT mastroenipietro immunologicalbasesofincreasedsusceptibilitytoinvasivenontyphoidalsalmonellainfectioninchildrenwithmalariaandanaemia

Ejemplares similares