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Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis
Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that controls inflammatory responses and redox homeostasis; however, its role during pulmonary tuberculosis (TB) remains unclear. Using freshly resected human TB lung tissue, we examined the role of HO-1 within the cellular and pathological spectrum...
Autores principales: | Chinta, Krishna C., Rahman, Md. Aejazur, Saini, Vikram, Glasgow, Joel N., Reddy, Vineel P., Lever, Jeremie M., Nhamoyebonde, Shepherd, Leslie, Alasdair, Wells, Ryan M., Traylor, Amie, Madansein, Rajhmun, Siegal, Gene P., Antony, Veena B., Deshane, Jessy, Wells, Gordon, Nargan, Kievershen, George, James F., Ramdial, Pratistadevi K., Agarwal, Anupam, Steyn, Adrie J.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250977/ https://www.ncbi.nlm.nih.gov/pubmed/30428359 http://dx.doi.org/10.1016/j.celrep.2018.10.073 |
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