Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

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Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that controls inflammatory responses and redox homeostasis; however, its role during pulmonary tuberculosis (TB) remains unclear. Using freshly resected human TB lung tissue, we examined the role of HO-1 within the cellular and pathological spectrum...

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Detalles Bibliográficos
Autores principales: Chinta, Krishna C., Rahman, Md. Aejazur, Saini, Vikram, Glasgow, Joel N., Reddy, Vineel P., Lever, Jeremie M., Nhamoyebonde, Shepherd, Leslie, Alasdair, Wells, Ryan M., Traylor, Amie, Madansein, Rajhmun, Siegal, Gene P., Antony, Veena B., Deshane, Jessy, Wells, Gordon, Nargan, Kievershen, George, James F., Ramdial, Pratistadevi K., Agarwal, Anupam, Steyn, Adrie J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250977/
https://www.ncbi.nlm.nih.gov/pubmed/30428359
http://dx.doi.org/10.1016/j.celrep.2018.10.073
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