Cargando…
The Role of VE-cadherin in Blood-brain Barrier Integrity under Central Nervous System Pathological Conditions
The blood-brain barrier (BBB) is a layer between the blood circulation and neural tissue. It plays a pivotal role in maintaining the vulnerable extracellular microenvironment in the neuronal parenchyma. Neuroinflammatory events can result in BBB dysregulation by disturbing adherens junctions (AJs) a...
Autores principales: | Li, Wenlu, Chen, Zhigang, Chin, Ian, Chen, Zhong, Dai, Haibin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251046/ https://www.ncbi.nlm.nih.gov/pubmed/29473514 http://dx.doi.org/10.2174/1570159X16666180222164809 |
Ejemplares similares
-
VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism
por: Juettner, Vanessa V., et al.
Publicado: (2019) -
Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
por: Knop, Juna-Lisa, et al.
Publicado: (2023) -
Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization
por: Navarro, Pilar, et al.
Publicado: (1998) -
VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
por: Nottebaum, Astrid F., et al.
Publicado: (2008) -
Regulation of endothelial barrier function by p120-catenin∙VE-cadherin interaction
por: Garrett, Joshua P., et al.
Publicado: (2017)