Helicobacter pylori CagA promotes epithelial mesenchymal transition in gastric carcinogenesis via triggering oncogenic YAP pathway

BACKGROUND: Helicobacter pylori (H. pylori) delivers oncoprotein CagA into gastric epithelial cells via the T4SS and drives activation of multiple oncogenic signalling pathways. YAP, a core effector of the Hippo tumour suppressor pathway, is frequently overexpressed in human cancers, suggesting its...

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Detalles Bibliográficos
Autores principales: Li, Nianshuang, Feng, Yan, Hu, Yi, He, Cong, Xie, Chuan, Ouyang, Yaobin, Artim, Stephen C., Huang, Deqiang, Zhu, Yin, Luo, Zhijun, Ge, Zhongming, Lu, Nonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251132/
https://www.ncbi.nlm.nih.gov/pubmed/30466467
http://dx.doi.org/10.1186/s13046-018-0962-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251132/
https://www.ncbi.nlm.nih.gov/pubmed/30466467
http://dx.doi.org/10.1186/s13046-018-0962-5

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