Methylome profiling of healthy and central precocious puberty girls

BACKGROUND: Recent studies demonstrated that changes in DNA methylation (DNAm) and inactivation of two imprinted genes (MKRN3 and DLK1) alter the onset of female puberty. We aimed to investigate the association of DNAm profiling with the timing of human puberty analyzing the genome-wide DNAm pattern...

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Detalles Bibliográficos
Autores principales: Bessa, Danielle S., Maschietto, Mariana, Aylwin, Carlos Francisco, Canton, Ana P. M., Brito, Vinicius N., Macedo, Delanie B., Cunha-Silva, Marina, Palhares, Heloísa M. C., de Resende, Elisabete A. M. R., Borges, Maria de Fátima, Mendonca, Berenice B., Netchine, Irene, Krepischi, Ana C. V., Lomniczi, Alejandro, Ojeda, Sergio R., Latronico, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251202/
https://www.ncbi.nlm.nih.gov/pubmed/30466473
http://dx.doi.org/10.1186/s13148-018-0581-1

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