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RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

BACKGROUND: Rearrangements of the anaplastic lymphoma kinase (ALK) belong to the promising targets in the therapy of advanced non-small cell lung cancer (NSCLC) and are predominantly detected by immunohistochemistry (IHC) and/or fluorescence in-situ hybridization (FISH). However, both methods occasi...

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Detalles Bibliográficos
Autores principales:	Vollbrecht, Claudia, Lenze, Dido, Hummel, Michael, Lehmann, Annika, Moebs, Markus, Frost, Nikolaj, Jurmeister, Philipp, Schweizer, Leonille, Kellner, Udo, Dietel, Manfred, von Laffert, Maximilian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251223/ https://www.ncbi.nlm.nih.gov/pubmed/30466405 http://dx.doi.org/10.1186/s12885-018-5070-6

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