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Precision Medicine: Changing the way we think about healthcare
Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251254/ https://www.ncbi.nlm.nih.gov/pubmed/30517307 http://dx.doi.org/10.6061/clinics/2017/e723 |
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author | Gameiro, Gustavo Rosa Sinkunas, Viktor Liguori, Gabriel Romero Auler-Júnior, José Otavio Costa |
author_facet | Gameiro, Gustavo Rosa Sinkunas, Viktor Liguori, Gabriel Romero Auler-Júnior, José Otavio Costa |
author_sort | Gameiro, Gustavo Rosa |
collection | PubMed |
description | Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it occurs and, if it cannot be avoided, treats the disease in a personalized manner. Precision Medicine is that new way of thinking about medicine. In this paper, we performed a thorough review of the literature to present an updated review on the subject, discussing the impact of the use of genetics and genomics in the care process as well as medical education, clinical research and ethical issues. The Precision Medicine model is expanded upon in this article to include its principles of prediction, prevention, personalization and participation. Finally, we discuss Precision Medicine in various specialty fields and how it has been implemented in developing countries and its effects on public health and medical education. |
format | Online Article Text |
id | pubmed-6251254 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-62512542018-11-29 Precision Medicine: Changing the way we think about healthcare Gameiro, Gustavo Rosa Sinkunas, Viktor Liguori, Gabriel Romero Auler-Júnior, José Otavio Costa Clinics (Sao Paulo) Review Article Health care has changed since the decline in mortality caused by infectious diseases as well as chronic and non-contagious diseases, with a direct impact on the cost of public health and individual health care. We must now transition from traditional reactive medicine based on symptoms, diagnosis and treatment to a system that targets the disease before it occurs and, if it cannot be avoided, treats the disease in a personalized manner. Precision Medicine is that new way of thinking about medicine. In this paper, we performed a thorough review of the literature to present an updated review on the subject, discussing the impact of the use of genetics and genomics in the care process as well as medical education, clinical research and ethical issues. The Precision Medicine model is expanded upon in this article to include its principles of prediction, prevention, personalization and participation. Finally, we discuss Precision Medicine in various specialty fields and how it has been implemented in developing countries and its effects on public health and medical education. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018-11-23 2018 /pmc/articles/PMC6251254/ /pubmed/30517307 http://dx.doi.org/10.6061/clinics/2017/e723 Text en Copyright © 2018 CLINICS http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited. |
spellingShingle | Review Article Gameiro, Gustavo Rosa Sinkunas, Viktor Liguori, Gabriel Romero Auler-Júnior, José Otavio Costa Precision Medicine: Changing the way we think about healthcare |
title | Precision Medicine: Changing the way we think about healthcare |
title_full | Precision Medicine: Changing the way we think about healthcare |
title_fullStr | Precision Medicine: Changing the way we think about healthcare |
title_full_unstemmed | Precision Medicine: Changing the way we think about healthcare |
title_short | Precision Medicine: Changing the way we think about healthcare |
title_sort | precision medicine: changing the way we think about healthcare |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251254/ https://www.ncbi.nlm.nih.gov/pubmed/30517307 http://dx.doi.org/10.6061/clinics/2017/e723 |
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