ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death

Amyotrophic Lateral Sclerosis (ALS) is a group of neurodegenerative disorders that featured with the death of motor neurons, which leads to loss of voluntary control on muscles. The etiologies vary among different subtypes of ALS, and no effective management or medication could be provided to the pa...

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Detalles Bibliográficos
Autores principales: Liu, Zhengzhao, Li, Hongming, Hong, Chungu, Chen, Menglu, Yue, Tao, Chen, Chunyuan, Wang, Zhenxing, You, Qing, Li, Chuanyin, Weng, Qinjie, Xie, Hui, Hu, Ronggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251386/
https://www.ncbi.nlm.nih.gov/pubmed/30519240
http://dx.doi.org/10.3389/fimmu.2018.02647

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