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In cellulo phosphorylation of DNA double-strand break repair protein XRCC4 on Ser260 by DNA-PK
XRCC4 is one of the core factors for DNA double-strand break (DSB) repair through non-homologous end joining (NHEJ). XRCC4 is phosphorylated by DNA-dependent protein kinase (DNA-PK), with Ser260 and Ser320 (Ser318 in the alternatively spliced form) being the major phosphorylation sites in vitro. It...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251426/ https://www.ncbi.nlm.nih.gov/pubmed/30247612 http://dx.doi.org/10.1093/jrr/rry072 |