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In cellulo phosphorylation of DNA double-strand break repair protein XRCC4 on Ser260 by DNA-PK

XRCC4 is one of the core factors for DNA double-strand break (DSB) repair through non-homologous end joining (NHEJ). XRCC4 is phosphorylated by DNA-dependent protein kinase (DNA-PK), with Ser260 and Ser320 (Ser318 in the alternatively spliced form) being the major phosphorylation sites in vitro. It...

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Detalles Bibliográficos
Autores principales:	Amiri Moghani, Ali Reza, Sharma, Mukesh Kumar, Matsumoto, Yoshihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Regular Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251426/ https://www.ncbi.nlm.nih.gov/pubmed/30247612 http://dx.doi.org/10.1093/jrr/rry072

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