Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts

BACKGROUND: Active, ligand-mediated, targeting of functionalized liposomes to folate receptors (FRs) overexpressed on cancer cells could potentially improve drug delivery and specificity. Studies on folate-targeting liposomes (FTLs) have, however, yielded varying results and generally fail to displa...

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Detalles Bibliográficos
Autores principales: Christensen, Esben, Henriksen, Jonas R, Jørgensen, Jesper T, Amitay, Yasmine, Shmeeda, Hilary, Gabizon, Alberto A, Kjær, Andreas, Andresen, Thomas L, Hansen, Anders E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251465/
https://www.ncbi.nlm.nih.gov/pubmed/30538449
http://dx.doi.org/10.2147/IJN.S182579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251465/
https://www.ncbi.nlm.nih.gov/pubmed/30538449
http://dx.doi.org/10.2147/IJN.S182579

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