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Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts

BACKGROUND: Active, ligand-mediated, targeting of functionalized liposomes to folate receptors (FRs) overexpressed on cancer cells could potentially improve drug delivery and specificity. Studies on folate-targeting liposomes (FTLs) have, however, yielded varying results and generally fail to displa...

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Detalles Bibliográficos
Autores principales:	Christensen, Esben, Henriksen, Jonas R, Jørgensen, Jesper T, Amitay, Yasmine, Shmeeda, Hilary, Gabizon, Alberto A, Kjær, Andreas, Andresen, Thomas L, Hansen, Anders E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251465/ https://www.ncbi.nlm.nih.gov/pubmed/30538449 http://dx.doi.org/10.2147/IJN.S182579

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