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Ascorbate peroxidase overexpression protects Leishmania braziliensis against trivalent antimony effects

Ascorbate peroxidase (APX) is a redox enzyme of the trypanothione pathway that converts hydrogen peroxide (H(2)O(2)) into water molecules. In the present study, the APX gene was overexpressed in Leishmania braziliensis to investigate its contribution to the trivalent antimony (Sb(III))-resistance ph...

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Detalles Bibliográficos
Autores principales: Moreira, Douglas de Souza, Xavier, Mariana Vieira, Murta/, Silvane Maria Fonseca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251480/
https://www.ncbi.nlm.nih.gov/pubmed/30507997
http://dx.doi.org/10.1590/0074-02760180377