Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery

DNA replication stress is often defined by the slowing or stalling of replication fork progression leading to local or global DNA synthesis inhibition. Failure to resolve replication stress in a timely manner contribute toward cell cycle defects, genome instability and human disease; however, the me...

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Detalles Bibliográficos
Autores principales: Tonzi, Peter, Yin, Yandong, Lee, Chelsea Wei Ting, Rothenberg, Eli, Huang, Tony T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251625/
https://www.ncbi.nlm.nih.gov/pubmed/30422114
http://dx.doi.org/10.7554/eLife.41426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251625/
https://www.ncbi.nlm.nih.gov/pubmed/30422114
http://dx.doi.org/10.7554/eLife.41426

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