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Targets and genomic constraints of ectopic Dnmt3b expression

DNA methylation plays an essential role in mammalian genomes and expression of the responsible enzymes is tightly controlled. Deregulation of the de novo DNA methyltransferase DNMT3B is frequently observed across cancer types, yet little is known about its ectopic genomic targets. Here, we used an i...

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Detalles Bibliográficos
Autores principales:	Zhang, Yingying, Charlton, Jocelyn, Karnik, Rahul, Beerman, Isabel, Smith, Zachary D, Gu, Hongcang, Boyle, Patrick, Mi, Xiaoli, Clement, Kendell, Pop, Ramona, Gnirke, Andreas, Rossi, Derrick J, Meissner, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251628/ https://www.ncbi.nlm.nih.gov/pubmed/30468428 http://dx.doi.org/10.7554/eLife.40757

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