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Media studies to enhance the production of verticillins facilitated by in situ chemical analysis
ABSTRACT: Verticillins are a group of epipolythiodioxopiperazine alkaloids that have displayed potent cytotoxicity. To evaluate their potential further, a larger supply of these compounds was needed for both in vivo studies and analogue development via semisynthesis. To optimize the biosynthesis of...
Autores principales: | Amrine, Chiraz Soumia M., Raja, Huzefa A., Darveaux, Blaise A., Pearce, Cedric J., Oberlies, Nicholas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251749/ https://www.ncbi.nlm.nih.gov/pubmed/30259213 http://dx.doi.org/10.1007/s10295-018-2083-8 |
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