C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death

Lysosomes are degradation and signaling centers within the cell, and their dysfunction impairs a wide variety of cellular processes. To understand the cellular effect of lysosome damage, we screened natural small-molecule compounds that induce lysosomal abnormality using Caenorhabditis elegans (C. e...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zhang, Yu, Gan, Qiwen, Xu, Meng, Ding, Xiao, Tang, Guihua, Liang, Jingjing, Liu, Kai, Liu, Xuezhao, Wang, Xin, Guo, Lingli, Gao, Zhiyang, Hao, Xiaojiang, Yang, Chonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251801/
https://www.ncbi.nlm.nih.gov/pubmed/29611115
http://dx.doi.org/10.1007/s13238-018-0520-0

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