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Arrestins: structural disorder creates rich functionality
Arrestins are soluble relatively small 44–46 kDa proteins that specifically bind hundreds of active phosphorylated GPCRs and dozens of non-receptor partners. There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microtubule-bou...
Autores principales: | Gurevich, Vsevolod V., Gurevich, Eugenia V., Uversky, Vladimir N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251804/ https://www.ncbi.nlm.nih.gov/pubmed/29453740 http://dx.doi.org/10.1007/s13238-017-0501-8 |
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