Cargando…
Energy landscape underlying spontaneous insertion and folding of an alpha-helical transmembrane protein into a bilayer
Membrane protein folding mechanisms and rates are notoriously hard to determine. A recent force spectroscopy study of the folding of an α-helical membrane protein, GlpG, showed that the folded state has a very high kinetic stability and a relatively low thermodynamic stability. Here, we simulate the...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251876/ https://www.ncbi.nlm.nih.gov/pubmed/30470737 http://dx.doi.org/10.1038/s41467-018-07320-9 |