Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity

The inflammasome plays a critical role in inflammation and immune responses against pathogens. However, whether or how inflammasome activation regulates type I interferon (IFN-I) signaling in the context of malaria infection remain unknown. Here we show mice deficient in inflammasome sensors AIM2, N...

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Detalles Bibliográficos
Autores principales: Yu, Xiao, Du, Yang, Cai, Chunmei, Cai, Baowei, Zhu, Motao, Xing, Changsheng, Tan, Peng, Lin, Meng, Wu, Jian, Li, Jian, Wang, Mingjun, Wang, Helen Y., Su, Xin-zhuan, Wang, Rong-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251914/
https://www.ncbi.nlm.nih.gov/pubmed/30470758
http://dx.doi.org/10.1038/s41467-018-07384-7

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