Whole genome amplification of cell-free DNA enables detection of circulating tumor DNA mutations from fingerstick capillary blood

The ability to measure mutations in plasma cell-free DNA (cfDNA) has the potential to revolutionize cancer surveillance and treatment by enabling longitudinal monitoring not possible with solid tumor biopsies. However, obtaining sufficient quantities of cfDNA remains a challenge for assay developmen...

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Detalles Bibliográficos
Autores principales: Gyanchandani, Rekha, Kvam, Erik, Heller, Ryan, Finehout, Erin, Smith, Nicholas, Kota, Karthik, Nelson, John R., Griffin, Weston, Puhalla, Shannon, Brufsky, Adam M., Davidson, Nancy E., Lee, Adrian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251935/
https://www.ncbi.nlm.nih.gov/pubmed/30470782
http://dx.doi.org/10.1038/s41598-018-35470-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251935/
https://www.ncbi.nlm.nih.gov/pubmed/30470782
http://dx.doi.org/10.1038/s41598-018-35470-9

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