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Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results

This study investigated the potential role of sex and handedness on the performance of a computerised Wisconsin Card Sorting Test (WCST) in healthy participants by applying functional near-infrared spectroscopy (fNIRS). We demonstrated significant (p < 0.05) sex-related differences of hemodynamic...

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Detalles Bibliográficos
Autores principales: Cinciute, Sigita, Daktariunas, Algis, Ruksenas, Osvaldas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252064/
https://www.ncbi.nlm.nih.gov/pubmed/30498629
http://dx.doi.org/10.7717/peerj.5890
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author Cinciute, Sigita
Daktariunas, Algis
Ruksenas, Osvaldas
author_facet Cinciute, Sigita
Daktariunas, Algis
Ruksenas, Osvaldas
author_sort Cinciute, Sigita
collection PubMed
description This study investigated the potential role of sex and handedness on the performance of a computerised Wisconsin Card Sorting Test (WCST) in healthy participants by applying functional near-infrared spectroscopy (fNIRS). We demonstrated significant (p < 0.05) sex-related differences of hemodynamic response in the prefrontal cortex of 70 healthy participants (female, n = 35 and male, n = 35; right-handed, n = 40 and left-handed, n = 30). In contrast, behavioural results of the WCST do not show sex bias, which is consistent with previous literature. Because of this, we compared ours and sparse previous fNIRS studies on the WCST. We propose that, according to recent studies of neurovascular coupling, this contradiction between neuroimaging and behavioural results may be explained by normal variability in neurovascular dynamics.
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spelling pubmed-62520642018-11-29 Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results Cinciute, Sigita Daktariunas, Algis Ruksenas, Osvaldas PeerJ Neuroscience This study investigated the potential role of sex and handedness on the performance of a computerised Wisconsin Card Sorting Test (WCST) in healthy participants by applying functional near-infrared spectroscopy (fNIRS). We demonstrated significant (p < 0.05) sex-related differences of hemodynamic response in the prefrontal cortex of 70 healthy participants (female, n = 35 and male, n = 35; right-handed, n = 40 and left-handed, n = 30). In contrast, behavioural results of the WCST do not show sex bias, which is consistent with previous literature. Because of this, we compared ours and sparse previous fNIRS studies on the WCST. We propose that, according to recent studies of neurovascular coupling, this contradiction between neuroimaging and behavioural results may be explained by normal variability in neurovascular dynamics. PeerJ Inc. 2018-11-21 /pmc/articles/PMC6252064/ /pubmed/30498629 http://dx.doi.org/10.7717/peerj.5890 Text en © 2018 Cinciute et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Neuroscience
Cinciute, Sigita
Daktariunas, Algis
Ruksenas, Osvaldas
Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title_full Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title_fullStr Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title_full_unstemmed Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title_short Hemodynamic effects of sex and handedness on the Wisconsin Card Sorting Test: the contradiction between neuroimaging and behavioural results
title_sort hemodynamic effects of sex and handedness on the wisconsin card sorting test: the contradiction between neuroimaging and behavioural results
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252064/
https://www.ncbi.nlm.nih.gov/pubmed/30498629
http://dx.doi.org/10.7717/peerj.5890
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