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Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation
BACKGROUND/AIMS: It is known that chronic low-grade inflammation contributes to the initiation and development of both diabetes and diabetic nephropathy (DN), so we designed this study to investigate the role of P2X7R and NLRP3 inflammasome in DN pathogenesis and the antagonistic effects of artifici...
Autores principales: | Wang, Chao, Hou, Xiao-xia, Rui, Hong-liang, Li, Li-jing, Zhao, Jing, Yang, Min, Sun, Li-jun, Dong, Hong-rui, Cheng, Hong, Chen, Yi-Pu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252193/ https://www.ncbi.nlm.nih.gov/pubmed/30534570 http://dx.doi.org/10.1155/2018/1390418 |
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