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Contribution of Neurons and Glial Cells to Complement-Mediated Synapse Removal during Development, Aging and in Alzheimer's Disease

Synapse loss is an early manifestation of pathology in Alzheimer's disease (AD) and is currently the best correlate to cognitive decline. Microglial cells are involved in synapse pruning during development via the complement pathway. Moreover, recent evidence points towards a key role played by...

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Detalles Bibliográficos
Autores principales:	Luchena, Celia, Zuazo-Ibarra, Jone, Alberdi, Elena, Matute, Carlos, Capetillo-Zarate, Estibaliz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252206/ https://www.ncbi.nlm.nih.gov/pubmed/30533998 http://dx.doi.org/10.1155/2018/2530414

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