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1379. Determination of the Arbekacin Exposure Required to Prevent Amplification of Resistant Subpopulations Using Patient Pharmacokinetics Simulated in a Hollow-Fiber Infection Model (HFIM)

BACKGROUND: ME1100 (arbekacin inhalational solution) is an aminoglycoside in clinical development for the treatment of patients with hospital-acquired and ventilator-associated bacterial pneumonia (HABP and VABP, respectively). Due to the increase in resistance of Staphylococcus aureus and Pseudomon...

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Detalles Bibliográficos
Autores principales:	VanScoy, Brian D, Lakota, Elizabeth A, Bhavnani, Sujata M, Giesel, Greg, Carranco, Ana I, Nagira, Yu, Ouchi, Shohei, Kondo, Kenichiro, Ambrose, Paul G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252722/ http://dx.doi.org/10.1093/ofid/ofy210.1210

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