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1584. Development and Dynamics of Cytomegalovirus UL97 Ganciclovir Resistance Mutations in Transplant Recipients Detected by Next-generation Sequencing
BACKGROUND: (Val)ganciclovir resistance mutations (GRMs) in CMV UL97 (UL97-GCV-R) complicate prophylaxis and therapy of solid-organ transplant (SOT) and hematopoietic (stem) cell transplant (HCT) recipients, but data on prevalence and dynamics are scarce. We investigated UL97-GCV-R using next-genera...
Autores principales: | Lodding, Isabelle Paula, Jørgensen, Mette, Bennedbæk, Marc, Kirkby, Nikolai, Naegele, Klaudia, Gustafsson, Finn, Perch, Michael, Rasmussen, Allan, Sengeløv, Henrik, Sørensen, Søren Schwartz, Hirsch, Hans, Lundgren, Jens D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252745/ http://dx.doi.org/10.1093/ofid/ofy210.1412 |
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