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1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study

BACKGROUND: Pharmacists have the authorization to prescribe medications for the treatment of uncomplicated urinary tract infections (UTI) in some Canadian provinces. However, there is limited data on the outcomes of this care by pharmacists. Our objective was to evaluate the effectiveness, safety, a...

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Autores principales: Beahm, Nathan, Smyth, Daniel, Tsuyuki, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252815/
http://dx.doi.org/10.1093/ofid/ofy210.1613
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author Beahm, Nathan
Smyth, Daniel
Tsuyuki, Ross
author_facet Beahm, Nathan
Smyth, Daniel
Tsuyuki, Ross
author_sort Beahm, Nathan
collection PubMed
description BACKGROUND: Pharmacists have the authorization to prescribe medications for the treatment of uncomplicated urinary tract infections (UTI) in some Canadian provinces. However, there is limited data on the outcomes of this care by pharmacists. Our objective was to evaluate the effectiveness, safety, and patient satisfaction with pharmacist prescribing and care in patients with uncomplicated UTI. METHODS: We conducted a prospective registry trial in 39 community pharmacies in the Canadian province of New Brunswick. Adult patients were enrolled if they presented to the pharmacy with either symptoms of UTI with no current antibacterial treatment (Pharmacist-Initial Arm) or if they presented with a prescription for an antibacterial to treat UTI from another healthcare provider (Physician-Initial Arm). Pharmacists assessed patients and if they had complicating factors or red flags for systemic illness or pyelonephritis, they were excluded from the study. Pharmacists either prescribed antibacterial therapy, modified antibacterial therapy, provided education only, or referred to physician, as appropriate. The primary outcome was clinical cure at 2 weeks and the secondary outcomes included adverse events and patient satisfaction. RESULTS: A total of 748 patients were enrolled (87% in the Pharmacist-Initial Arm), average age was 40.8 (SD 15.9) years. Clinical cure was achieved in 89% of patients. Of those that did not have sustained symptom resolution, most (6% overall) had symptom recurrence after completion of therapy. Adverse events were reported by 7% of patients and 88% of those continued their medication. Most adverse events were gastrointestinal-related and transient. The patient satisfaction survey reflected very high levels of satisfaction for the care they received, as well as for trust and accessibility of the pharmacist. CONCLUSION: Pharmacist management of uncomplicated UTI is effective, safe, and patient satisfaction is very high. DISCLOSURES: All authors: No reported disclosures.
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spelling pubmed-62528152018-11-28 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study Beahm, Nathan Smyth, Daniel Tsuyuki, Ross Open Forum Infect Dis Abstracts BACKGROUND: Pharmacists have the authorization to prescribe medications for the treatment of uncomplicated urinary tract infections (UTI) in some Canadian provinces. However, there is limited data on the outcomes of this care by pharmacists. Our objective was to evaluate the effectiveness, safety, and patient satisfaction with pharmacist prescribing and care in patients with uncomplicated UTI. METHODS: We conducted a prospective registry trial in 39 community pharmacies in the Canadian province of New Brunswick. Adult patients were enrolled if they presented to the pharmacy with either symptoms of UTI with no current antibacterial treatment (Pharmacist-Initial Arm) or if they presented with a prescription for an antibacterial to treat UTI from another healthcare provider (Physician-Initial Arm). Pharmacists assessed patients and if they had complicating factors or red flags for systemic illness or pyelonephritis, they were excluded from the study. Pharmacists either prescribed antibacterial therapy, modified antibacterial therapy, provided education only, or referred to physician, as appropriate. The primary outcome was clinical cure at 2 weeks and the secondary outcomes included adverse events and patient satisfaction. RESULTS: A total of 748 patients were enrolled (87% in the Pharmacist-Initial Arm), average age was 40.8 (SD 15.9) years. Clinical cure was achieved in 89% of patients. Of those that did not have sustained symptom resolution, most (6% overall) had symptom recurrence after completion of therapy. Adverse events were reported by 7% of patients and 88% of those continued their medication. Most adverse events were gastrointestinal-related and transient. The patient satisfaction survey reflected very high levels of satisfaction for the care they received, as well as for trust and accessibility of the pharmacist. CONCLUSION: Pharmacist management of uncomplicated UTI is effective, safe, and patient satisfaction is very high. DISCLOSURES: All authors: No reported disclosures. Oxford University Press 2018-11-26 /pmc/articles/PMC6252815/ http://dx.doi.org/10.1093/ofid/ofy210.1613 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Abstracts
Beahm, Nathan
Smyth, Daniel
Tsuyuki, Ross
1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title_full 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title_fullStr 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title_full_unstemmed 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title_short 1957. Pharmacist Prescribing and Care in Patients with Uncomplicated Urinary Tract Infections in the Community: Efficacy and Safety Outcomes of the R(x)OUTMAP Study
title_sort 1957. pharmacist prescribing and care in patients with uncomplicated urinary tract infections in the community: efficacy and safety outcomes of the r(x)outmap study
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252815/
http://dx.doi.org/10.1093/ofid/ofy210.1613
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