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1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers

BACKGROUND: The patient-centered HIV care model was developed to integrate community pharmacists with HIV clinical providers to deliver patient-centered HIV care. The project required 10 clinics to share, with their partnered community-based pharmacists, patients’ medical histories, laboratory resul...

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Autores principales: Byrd, Kathy, Hou, John, Clay, Patrick, Bush, Tim, Delpino, Ambrose, Shankle, Michael, Camp, Nasima, Kirkham, Heather, Hazen, Ronald, Weidle, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253032/
http://dx.doi.org/10.1093/ofid/ofy209.154
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author Byrd, Kathy
Hou, John
Clay, Patrick
Bush, Tim
Delpino, Ambrose
Shankle, Michael
Camp, Nasima
Kirkham, Heather
Hazen, Ronald
Weidle, Paul
author_facet Byrd, Kathy
Hou, John
Clay, Patrick
Bush, Tim
Delpino, Ambrose
Shankle, Michael
Camp, Nasima
Kirkham, Heather
Hazen, Ronald
Weidle, Paul
author_sort Byrd, Kathy
collection PubMed
description BACKGROUND: The patient-centered HIV care model was developed to integrate community pharmacists with HIV clinical providers to deliver patient-centered HIV care. The project required 10 clinics to share, with their partnered community-based pharmacists, patients’ medical histories, laboratory results, and medications. Pharmacists reviewed the clinic data and worked directly with participants and/or their partnered clinics to make recommendations and discuss potential intervention strategies for identified therapy-related problems. METHODS: We calculated the proportion of persons virally suppressed (<200 copies/mL at the last test in each of two 12-month measurement periods), pre- and post-model implementation. Included in the analysis were persons with ≥1 HIV viral load in each measurement period. McNemar’s test was used to compare the proportion virally suppressed, pre- and postimplementation. Multivariable logistic regression was used to determine factors associated with viral suppression, postimplementation. Participant demographics and the proportion of days covered (PDC; a measure used to calculate adherence to medication therapy) were used as explanatory variables in the model. The PDC was modified to account for the time to the last viral load in the measurement period, and was stratified into 4 categories: ≥90%, <90–80%, <80–50%, and <50%. RESULTS: With 765 persons enrolled, the plurality of those included in the analysis (n = 648) were non-Hispanic black (n = 286), male (n = 470), and had a median age of 49 years (IQR=38–56). Viral suppression improved 16.3% from 73.9% to 85.9%, pre- to postimplementation (P < 0.001). Persons who had higher modified PDC (OR 1.9 per category level; 95% CI 1.4–2.6), were currently employed (OR 4.1; 1.6–12.8), or age >50 years (OR 4.7; 2.1–11.8), had greater odds of being suppressed. Non-Hispanic black persons were less likely to be suppressed (OR 0.2; 0.1–0.6); however, viral suppression among this group improved from 62.5% to 77.6%, pre- to postimplementation (P < 0.001). CONCLUSION: Collaborations between community pharmacists and HIV clinic providers that seek to identify and address HIV therapy-related problems can lead to improved viral suppression among persons living with HIV. DISCLOSURES: P. Clay, Jaguar Health, Inc.: Consultant and Speaker’s Bureau, Consulting fee and Speaker honorarium. Merck & Co., Inc.: Investigator, Research grant. A. Delpino, Walgreens: Employee and Shareholder, Salary.
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spelling pubmed-62530322018-11-28 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers Byrd, Kathy Hou, John Clay, Patrick Bush, Tim Delpino, Ambrose Shankle, Michael Camp, Nasima Kirkham, Heather Hazen, Ronald Weidle, Paul Open Forum Infect Dis Abstracts BACKGROUND: The patient-centered HIV care model was developed to integrate community pharmacists with HIV clinical providers to deliver patient-centered HIV care. The project required 10 clinics to share, with their partnered community-based pharmacists, patients’ medical histories, laboratory results, and medications. Pharmacists reviewed the clinic data and worked directly with participants and/or their partnered clinics to make recommendations and discuss potential intervention strategies for identified therapy-related problems. METHODS: We calculated the proportion of persons virally suppressed (<200 copies/mL at the last test in each of two 12-month measurement periods), pre- and post-model implementation. Included in the analysis were persons with ≥1 HIV viral load in each measurement period. McNemar’s test was used to compare the proportion virally suppressed, pre- and postimplementation. Multivariable logistic regression was used to determine factors associated with viral suppression, postimplementation. Participant demographics and the proportion of days covered (PDC; a measure used to calculate adherence to medication therapy) were used as explanatory variables in the model. The PDC was modified to account for the time to the last viral load in the measurement period, and was stratified into 4 categories: ≥90%, <90–80%, <80–50%, and <50%. RESULTS: With 765 persons enrolled, the plurality of those included in the analysis (n = 648) were non-Hispanic black (n = 286), male (n = 470), and had a median age of 49 years (IQR=38–56). Viral suppression improved 16.3% from 73.9% to 85.9%, pre- to postimplementation (P < 0.001). Persons who had higher modified PDC (OR 1.9 per category level; 95% CI 1.4–2.6), were currently employed (OR 4.1; 1.6–12.8), or age >50 years (OR 4.7; 2.1–11.8), had greater odds of being suppressed. Non-Hispanic black persons were less likely to be suppressed (OR 0.2; 0.1–0.6); however, viral suppression among this group improved from 62.5% to 77.6%, pre- to postimplementation (P < 0.001). CONCLUSION: Collaborations between community pharmacists and HIV clinic providers that seek to identify and address HIV therapy-related problems can lead to improved viral suppression among persons living with HIV. DISCLOSURES: P. Clay, Jaguar Health, Inc.: Consultant and Speaker’s Bureau, Consulting fee and Speaker honorarium. Merck & Co., Inc.: Investigator, Research grant. A. Delpino, Walgreens: Employee and Shareholder, Salary. Oxford University Press 2018-11-26 /pmc/articles/PMC6253032/ http://dx.doi.org/10.1093/ofid/ofy209.154 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Abstracts
Byrd, Kathy
Hou, John
Clay, Patrick
Bush, Tim
Delpino, Ambrose
Shankle, Michael
Camp, Nasima
Kirkham, Heather
Hazen, Ronald
Weidle, Paul
1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title_full 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title_fullStr 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title_full_unstemmed 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title_short 1769. Viral Suppression Among Participants of the Patient-Centered HIV Care Model Project—A Collaboration Between Community-Based Pharmacists and HIV Clinical Providers
title_sort 1769. viral suppression among participants of the patient-centered hiv care model project—a collaboration between community-based pharmacists and hiv clinical providers
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253032/
http://dx.doi.org/10.1093/ofid/ofy209.154
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