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1955. A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin vs. Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants ≤3 Months of Age

BACKGROUND: Candida species are the most common fungal pathogens in infants aged <1 year. Current antifungal regimens such as amphotericin B deoxycholate (dAmB) are associated with serious toxicity and multiple drug-drug interactions. The echinocandin caspofungin has less toxicity than dAmB and i...

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Detalles Bibliográficos
Autores principales: Kim, Jason, Nakwa, Firdose Lambey, Motta, Fábio De Araujo, Lozada, Perla Salcedo, Alabaz, Derya, Liu, Hong, Bloise, Keisha, Dorr, Mary Beth, Gaffney, Leah J Anderson, Kartsonis, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253098/
http://dx.doi.org/10.1093/ofid/ofy210.1611