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963. Whole Blood Transcriptome Analysis Reveals Differences in Erythropoiesis and Neurologically Relevant Pathways Between Cerebral Malaria and Severe Malarial Anemia

BACKGROUND: Plasmodium falciparum malaria can rapidly progress to severe disease that can lead to death if left untreated. Severe malaria cases commonly present as severe malarial anemia (SMA), defined in children as hemoglobin (Hb) <5 g/dL with parasitemia, or as cerebral malaria (CM), which man...

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Detalles Bibliográficos
Autores principales: Nallandhighal, Srinivas, Park, Gregory, Ho, Yen-Yi, Opoka, Robert, John, Chandy, Tran, Tuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253137/
http://dx.doi.org/10.1093/ofid/ofy209.079