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802. Use of N-Acetylcysteine for Prevention and Treatment of Isoniazid Induced Liver Injury During Treatment of Mycobacterial Infections

BACKGROUND: Hepatotoxicity secondary to therapy for Mycobacterium tuberculosis (MTB) is a common complication that may lead to treatment interruption. N-Acetylcysteine (NAC) exerts a hepatoprotective effect by repleting glutathione stores and enhancing the cellular antioxidant defense mechanism. NAC...

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Detalles Bibliográficos
Autores principales:	Diaz, Heidi Torres, Serrano, Ruth, Bowling, Jason E, Anstead, Gregory, Javeri, Heta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253180/ http://dx.doi.org/10.1093/ofid/ofy210.809

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