Thermus thermophilus Strains Active in Purine Nucleoside Synthesis

Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases. High productivity values (t =1 hr) were obtained while completely avoiding adenosine-deaminase degradation...

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Autores principales: Almendros, Marcos, Gago, José-Vicente Sinisterra, Carlos, José Berenguer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253774/
https://www.ncbi.nlm.nih.gov/pubmed/19325523
http://dx.doi.org/10.3390/molecules14031279
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author Almendros, Marcos
Gago, José-Vicente Sinisterra
Carlos, José Berenguer
author_facet Almendros, Marcos
Gago, José-Vicente Sinisterra
Carlos, José Berenguer
author_sort Almendros, Marcos
collection PubMed
description Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases. High productivity values (t =1 hr) were obtained while completely avoiding adenosine-deaminase degradation of the products. N-2-deoxy-ribosyltransferase activity is described for the first time in hyperthermophilic bacteria.
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spelling pubmed-62537742018-11-30 Thermus thermophilus Strains Active in Purine Nucleoside Synthesis Almendros, Marcos Gago, José-Vicente Sinisterra Carlos, José Berenguer Molecules Article Several strains of Thermus thermophilus were tested in order to detect purine nucleoside synthase activity using pyrimidine nucleosides as the sugar-donor and adenine or hypoxanthine as bases. High productivity values (t =1 hr) were obtained while completely avoiding adenosine-deaminase degradation of the products. N-2-deoxy-ribosyltransferase activity is described for the first time in hyperthermophilic bacteria. Molecular Diversity Preservation International 2009-03-24 /pmc/articles/PMC6253774/ /pubmed/19325523 http://dx.doi.org/10.3390/molecules14031279 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Almendros, Marcos
Gago, José-Vicente Sinisterra
Carlos, José Berenguer
Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title_full Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title_fullStr Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title_full_unstemmed Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title_short Thermus thermophilus Strains Active in Purine Nucleoside Synthesis
title_sort thermus thermophilus strains active in purine nucleoside synthesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253774/
https://www.ncbi.nlm.nih.gov/pubmed/19325523
http://dx.doi.org/10.3390/molecules14031279
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AT carlosjoseberenguer thermusthermophilusstrainsactiveinpurinenucleosidesynthesis

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