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Effects of CDX2 on prognosis and chemotherapy responsiveness in mismatch repair‐deficient colorectal cancer
BACKGROUND: Caudal‐related homeobox transcription factor 2 (CDX2) is an intestine‐specific transcription factor implicated in tumour differentiation, proliferation, cell adhesion and migration. Negative CDX2 status (CDX2−) is associated with worse prognosis in colorectal cancer and may identify high...
Autores principales: | Ryan, É. J., Creavin, B., Khaw, Y. L., Kelly, M. E., Mohan, H. M., Geraghty, R., Ryan, E. J., Kennelly, R., Hanly, A., Martin, S. T., Fennelly, D., McDermott, R., Gibbons, D., O'Connell, P. R, Sheahan, K., Winter, D. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253792/ https://www.ncbi.nlm.nih.gov/pubmed/30511046 http://dx.doi.org/10.1002/bjs5.91 |
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