Total Syntheses of Telisatin A, Telisatin B and Lettowianthine

Treatment of 1-(2-bromoarylmethyl)-3,4-dihydroisoquinolines with oxalyl chloride and triethylamine gave 1-(2-bromophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2,3-dione derivatives, for example, 1-(2-bromophenyl)-5,6-dihydro-8,9-dimethoxypyrrolo[2,1-a]isoquinoline-2,3-dione. Radical cyclisation of...

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Detalles Bibliográficos
Autores principales: Nimgirawath, Surachai, Udomputtimekakul, Phansuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253876/
https://www.ncbi.nlm.nih.gov/pubmed/19255550
http://dx.doi.org/10.3390/molecules14030917
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author Nimgirawath, Surachai
Udomputtimekakul, Phansuang
author_facet Nimgirawath, Surachai
Udomputtimekakul, Phansuang
author_sort Nimgirawath, Surachai
collection PubMed
description Treatment of 1-(2-bromoarylmethyl)-3,4-dihydroisoquinolines with oxalyl chloride and triethylamine gave 1-(2-bromophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2,3-dione derivatives, for example, 1-(2-bromophenyl)-5,6-dihydro-8,9-dimethoxypyrrolo[2,1-a]isoquinoline-2,3-dione. Radical cyclisation of these derivatives with tributyltin hydride and 1,1ʹ-azobis(cyclohexanecarbonitrile) afforded telisatin A, telisatin B and lettowianthine.
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spelling pubmed-62538762018-11-30 Total Syntheses of Telisatin A, Telisatin B and Lettowianthine Nimgirawath, Surachai Udomputtimekakul, Phansuang Molecules Article Treatment of 1-(2-bromoarylmethyl)-3,4-dihydroisoquinolines with oxalyl chloride and triethylamine gave 1-(2-bromophenyl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2,3-dione derivatives, for example, 1-(2-bromophenyl)-5,6-dihydro-8,9-dimethoxypyrrolo[2,1-a]isoquinoline-2,3-dione. Radical cyclisation of these derivatives with tributyltin hydride and 1,1ʹ-azobis(cyclohexanecarbonitrile) afforded telisatin A, telisatin B and lettowianthine. Molecular Diversity Preservation International 2009-02-26 /pmc/articles/PMC6253876/ /pubmed/19255550 http://dx.doi.org/10.3390/molecules14030917 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Nimgirawath, Surachai
Udomputtimekakul, Phansuang
Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title_full Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title_fullStr Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title_full_unstemmed Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title_short Total Syntheses of Telisatin A, Telisatin B and Lettowianthine
title_sort total syntheses of telisatin a, telisatin b and lettowianthine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253876/
https://www.ncbi.nlm.nih.gov/pubmed/19255550
http://dx.doi.org/10.3390/molecules14030917
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