A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha

A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their struc...

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Detalles Bibliográficos
Autores principales: Wang, Zhan Chang, Lin, Yi Ming, Feng, Dan Qin, Ke, Cai Huan, Lin, Peng, Yan, Chong Ling, Chen, Jun De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253882/
https://www.ncbi.nlm.nih.gov/pubmed/19158653
http://dx.doi.org/10.3390/molecules14010414
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author Wang, Zhan Chang
Lin, Yi Ming
Feng, Dan Qin
Ke, Cai Huan
Lin, Peng
Yan, Chong Ling
Chen, Jun De
author_facet Wang, Zhan Chang
Lin, Yi Ming
Feng, Dan Qin
Ke, Cai Huan
Lin, Peng
Yan, Chong Ling
Chen, Jun De
author_sort Wang, Zhan Chang
collection PubMed
description A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC(50) value of 0.54 ± 0.01 ppm.
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spelling pubmed-62538822018-11-30 A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha Wang, Zhan Chang Lin, Yi Ming Feng, Dan Qin Ke, Cai Huan Lin, Peng Yan, Chong Ling Chen, Jun De Molecules Communication A new atisane-type diterpene, ent-16α-hydroxy-atisane-3,4-lactone (4) and three known diterpenes, ent-16α-hydroxy-atisane-3-one (1), ent-atisane-3β,16α-diol (2), ent-3,4-seco-16α-hydroxyatis- 4(19)-en -3-oic acid (3) were isolated from the bark of the mangrove plant Excoecaria agallocha. Their structures and relative stereochemistry were elucidated by means of extensive NMR and MS analysis. Compound 3 exhibited significant anti-microfouling activity against the adherence of Pseudomonas pseudoalcaligenes, with an EC(50) value of 0.54 ± 0.01 ppm. Molecular Diversity Preservation International 2009-01-16 /pmc/articles/PMC6253882/ /pubmed/19158653 http://dx.doi.org/10.3390/molecules14010414 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Wang, Zhan Chang
Lin, Yi Ming
Feng, Dan Qin
Ke, Cai Huan
Lin, Peng
Yan, Chong Ling
Chen, Jun De
A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title_full A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title_fullStr A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title_full_unstemmed A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title_short A New Atisane-Type Diterpene from the Bark of the Mangrove Plant Excoecaria Agallocha
title_sort new atisane-type diterpene from the bark of the mangrove plant excoecaria agallocha
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253882/
https://www.ncbi.nlm.nih.gov/pubmed/19158653
http://dx.doi.org/10.3390/molecules14010414
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