Cargando…
Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents
Prodrug design for brain delivery of small- and medium-sized neuropeptides was reviewed, focusing on thyrotropin-releasing hormone and structurally related peptides as examples. We have summarized our most important advances in methodology, as well as assessed the benefits and limitations of bioreve...
Autores principales: | Prokai-Tatrai, Katalin, Prokai, Laszlo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253886/ https://www.ncbi.nlm.nih.gov/pubmed/19214153 http://dx.doi.org/10.3390/molecules14020633 |
Ejemplares similares
-
Design and Exploratory Neuropharmacological Evaluation of Novel Thyrotropin-Releasing Hormone Analogs and Their Brain-Targeting Bioprecursor Prodrugs
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2013) -
Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019) -
A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019) -
[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021) -
The Antagonist pGlu-βGlu-Pro-NH(2) Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor
por: De La Cruz, Daniel L., et al.
Publicado: (2021)