Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7

SIRT7 is one of seven mammalian sirtuins that functions as an NAD(+)-dependent histone/protein deacetylase. SIRT7 is the least well-known member of the sirtuin family, but recent efforts have identified its involvement in various cellular processes, such as ribosome biogenesis, gene expression, cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Di, Li, Yinglu, Zhu, Kathy S., Wang, Haiying, Zhu, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253933/
https://www.ncbi.nlm.nih.gov/pubmed/30510540
http://dx.doi.org/10.3389/fendo.2018.00652
_version_ 1783373608388657152
author Wu, Di
Li, Yinglu
Zhu, Kathy S.
Wang, Haiying
Zhu, Wei-Guo
author_facet Wu, Di
Li, Yinglu
Zhu, Kathy S.
Wang, Haiying
Zhu, Wei-Guo
author_sort Wu, Di
collection PubMed
description SIRT7 is one of seven mammalian sirtuins that functions as an NAD(+)-dependent histone/protein deacetylase. SIRT7 is the least well-known member of the sirtuin family, but recent efforts have identified its involvement in various cellular processes, such as ribosome biogenesis, gene expression, cellular metabolism and cancer. Here we provide an update on the functions and mechanisms of SIRT7 in cellular regulation and disease.
format Online
Article
Text
id pubmed-6253933
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-62539332018-12-03 Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7 Wu, Di Li, Yinglu Zhu, Kathy S. Wang, Haiying Zhu, Wei-Guo Front Endocrinol (Lausanne) Endocrinology SIRT7 is one of seven mammalian sirtuins that functions as an NAD(+)-dependent histone/protein deacetylase. SIRT7 is the least well-known member of the sirtuin family, but recent efforts have identified its involvement in various cellular processes, such as ribosome biogenesis, gene expression, cellular metabolism and cancer. Here we provide an update on the functions and mechanisms of SIRT7 in cellular regulation and disease. Frontiers Media S.A. 2018-11-19 /pmc/articles/PMC6253933/ /pubmed/30510540 http://dx.doi.org/10.3389/fendo.2018.00652 Text en Copyright © 2018 Wu, Li, Zhu, Wang and Zhu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Wu, Di
Li, Yinglu
Zhu, Kathy S.
Wang, Haiying
Zhu, Wei-Guo
Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title_full Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title_fullStr Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title_full_unstemmed Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title_short Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7
title_sort advances in cellular characterization of the sirtuin isoform, sirt7
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253933/
https://www.ncbi.nlm.nih.gov/pubmed/30510540
http://dx.doi.org/10.3389/fendo.2018.00652
work_keys_str_mv AT wudi advancesincellularcharacterizationofthesirtuinisoformsirt7
AT liyinglu advancesincellularcharacterizationofthesirtuinisoformsirt7
AT zhukathys advancesincellularcharacterizationofthesirtuinisoformsirt7
AT wanghaiying advancesincellularcharacterizationofthesirtuinisoformsirt7
AT zhuweiguo advancesincellularcharacterizationofthesirtuinisoformsirt7

Ejemplares similares