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Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis

The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete (1)H- and (13)C...

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Detalles Bibliográficos
Autores principales: Mukhtar, Mat Ropi, Aziz, Ahmad Nazif, Thomas, Noel F., Hadi, A. Hamid A., Litaudon, Marc, Awang, Khalijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253996/
https://www.ncbi.nlm.nih.gov/pubmed/19325519
http://dx.doi.org/10.3390/molecules14031227
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author Mukhtar, Mat Ropi
Aziz, Ahmad Nazif
Thomas, Noel F.
Hadi, A. Hamid A.
Litaudon, Marc
Awang, Khalijah
author_facet Mukhtar, Mat Ropi
Aziz, Ahmad Nazif
Thomas, Noel F.
Hadi, A. Hamid A.
Litaudon, Marc
Awang, Khalijah
author_sort Mukhtar, Mat Ropi
collection PubMed
description The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete (1)H- and (13)C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data.
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spelling pubmed-62539962018-11-30 Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis Mukhtar, Mat Ropi Aziz, Ahmad Nazif Thomas, Noel F. Hadi, A. Hamid A. Litaudon, Marc Awang, Khalijah Molecules Article The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete (1)H- and (13)C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data. Molecular Diversity Preservation International 2009-03-23 /pmc/articles/PMC6253996/ /pubmed/19325519 http://dx.doi.org/10.3390/molecules14031227 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Mukhtar, Mat Ropi
Aziz, Ahmad Nazif
Thomas, Noel F.
Hadi, A. Hamid A.
Litaudon, Marc
Awang, Khalijah
Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_full Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_fullStr Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_full_unstemmed Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_short Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_sort grandine a, a new proaporphine alkaloid from the bark of phoebe grandis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253996/
https://www.ncbi.nlm.nih.gov/pubmed/19325519
http://dx.doi.org/10.3390/molecules14031227
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