Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones

A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields...

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Detalles Bibliográficos
Autores principales: Liu, Chen-Jiang, Wang, Ji-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254017/
https://www.ncbi.nlm.nih.gov/pubmed/19223824
http://dx.doi.org/10.3390/molecules14020763
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author Liu, Chen-Jiang
Wang, Ji-De
author_facet Liu, Chen-Jiang
Wang, Ji-De
author_sort Liu, Chen-Jiang
collection PubMed
description A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity.
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spelling pubmed-62540172018-11-30 Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones Liu, Chen-Jiang Wang, Ji-De Molecules Article A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity. Molecular Diversity Preservation International 2009-02-13 /pmc/articles/PMC6254017/ /pubmed/19223824 http://dx.doi.org/10.3390/molecules14020763 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Liu, Chen-Jiang
Wang, Ji-De
Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title_full Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title_fullStr Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title_full_unstemmed Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title_short Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones
title_sort copper(ii) sulfamate: an efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidine-2(1h)-ones and thiones
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254017/
https://www.ncbi.nlm.nih.gov/pubmed/19223824
http://dx.doi.org/10.3390/molecules14020763
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